Adjusting microbiome profiles for differences in microbial load by spike-in bacteria
نویسندگان
چکیده
منابع مشابه
Adjusting microbiome profiles for differences in microbial load by spike-in bacteria
BACKGROUND Next-generation 16S ribosomal RNA gene sequencing is widely used to determine the relative composition of the mammalian gut microbiomes. However, in the absence of a reference, this does not reveal alterations in absolute abundance of specific operational taxonomic units if microbial loads vary across specimens. RESULTS Here we suggest the spiking of exogenous bacteria into crude s...
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ژورنال
عنوان ژورنال: Microbiome
سال: 2016
ISSN: 2049-2618
DOI: 10.1186/s40168-016-0175-0